The National Soccer League 1980 season was the fourth season of the National Soccer League in Australia. The champions were Sydney City SC, their second title after winning the 1977 season (as Eastern Suburbs).
| Pos | Club | P | W | D | L | GF | GA | Pts |
| 1 | Sydney City | 26 | 16 | 5 | 5 | 51 | 26 | 37 |
| 2 | Heidelberg United | 26 | 15 | 6 | 5 | 55 | 33 | 36 |
| 3 | South Melbourne | 26 | 15 | 5 | 6 | 42 | 21 | 35 |
| 4 | Marconi Fairfield | 26 | 14 | 6 | 6 | 53 | 32 | 34 |
| 5 | Adelaide City | 26 | 13 | 4 | 9 | 40 | 27 | 30 |
| 6 | Newcastle KB United | 26 | 12 | 6 | 8 | 32 | 31 | 30 |
| 7 | Brisbane Lions | 26 | 7 | 11 | 8 | 28 | 32 | 25 |
| 8 | A.P.I.A. Leichhardt Tigers | 26 | 8 | 7 | 11 | 27 | 35 | 23 |
| 9 | Footscray JUST | 26 | 7 | 9 | 10 | 32 | 41 | 23 |
| 10 | Canberra City | 26 | 7 | 7 | 12 | 34 | 33 | 21 |
| 11 | Blacktown City | 26 | 9 | 3 | 14 | 34 | 55 | 21 |
| 12 | Brisbane City | 26 | 4 | 10 | 12 | 29 | 36 | 18 |
| 13 | West Adelaide | 26 | 7 | 3 | 16 | 24 | 46 | 17 |
| 14 | St George Saints | 26 | 5 | 4 | 17 | 32 | 65 | 14 |